Gene therapy targets epilepsy

Gene therapy for epilepsy.

Gene therapy may represent an effective alternative to standard pharmacological approaches for certain forms of epilepsy. Currently, the best candidates for this therapeutic approach appear to be epilepsies characterized by a focal lesion. Gene therapy has been attempted to produce antiepileptogenic (prevention of development of epilepsy in subject at risk after having received an epileptogenic...

Choosing Targets for Gene Therapy

Gene therapy for arthritis: defining novel gene targets

Gene Therapy for Epilepsy: Resculpturing Synaptic Transmission with Neuropeptides

Recombinant adeno-associated viral (rAAV) vector-induced neuropeptide Y (NPY) overexpression in the hippocampusexerts powerful antiepileptic and antiepileptogenic effects in rats. Suchgene therapy approach could be a valuable alternative for developingnew antiepileptic treatment strategies. Future clinical progress, how-ever, requires more detailed evaluation of possible sid...

Genetic models of retinal degeneration and targets for gene therapy

*Correspondence: Stephen H. Tsang, M.D., Ph.D., Columbia College of Physicians & Surgeons, Harkness Eye Institute Research Annex 513, 160 Fort Washington Avenue, New York, NY 10032. Tel: (212)-342-1189, Fax: (212)-305-4987, Email: [email protected]